RS3PE syndrome. The relation with HLA B7

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Syndrome of remitting seronegative symmetrical synovitis with pitting oedema (RS3PE).

RS3PE syndrome, often mimicking rheumatoid arthritis (RA) or polymyalgia rheumatica (PMR), has puzzled the rheumatologists until late'80s. Though the nature of the disease still remains illusive, the outcome is excellent. This present study analyzes the clinical, radiological and immunogenetical characteristics of five patients diagnosed with RS3PE syndrome, with review of literature.

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Remitting seronegative symmetrical synovitis with pitting edema (RS3PE syndrome).

A 63-year-old man presented with acute symmetrical polysynovitis associated with pitting edema of both the hands and feet. He was seronegative for rheumatoid factor and no radiologically evident erosion was noted in the joints of his hands and feet. Evaluation excluded congestive heart failure, nephrotic syndrome, and hypothyroidism as the cause of edema. Treatment with nonsteroidal anti-inflam...

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Familial aggregation of undifferentiated spondyloarthropathy associated with HLA-B7.

OBJECTIVE To report multiple cases of recurrent seronegative arthropathy, enthesopathy, or both, occurring in a single family in the absence of the HLA-B27 tissue type, coexistent psoriasis or inflammatory bowel disease. METHODS Three generations of one family together with their general practitioners completed a standard questionnaire. All subjects with a positive questionnaire and two rando...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 2000

ISSN: 0003-4967

DOI: 10.1136/ard.59.3.239a